| <P><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">《中国新药杂志》上的一项临床研究显示，喹硫平可用于治疗伴强迫症状精神分裂症患者。</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /><o:p></o:p></SPAN></P>
<P><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">此项研究采用多中心、自身前后对照试验，选择</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">58</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">例符合</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">ICD-10</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">诊断标准的精神分裂症患者，接受可变剂量的喹硫平治疗</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">8</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">周。</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><o:p></o:p></SPAN></P>
<P><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">结果发现，完成治疗患者的耶鲁</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">-</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">布朗强迫症状量表</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">(Y-BOCS)</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">、阳性及阴性症状量表</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">(PANSS)</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">评分在治疗前后均差异有统计学意义。</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">8</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">周末强迫症状的有效率为</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">63.3%</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">，精神病性症状有效率为</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">65.3%</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">。不良反应有心动过速、体位性低血压、肝功能轻微异常等。</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><o:p></o:p></SPAN></P>
<P><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><o:p> </o:p></SPAN></P> |
