| <P style="BACKGROUND: white; MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 24pt; TEXT-ALIGN: left; mso-line-height-alt: 0pt; mso-char-indent-count: 2.0; mso-pagination: widow-orphan" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">据彭博新闻网</SPAN> <SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: Arial; mso-font-kerning: 0pt; mso-ansi-language: en" XML:LANG="EN">10</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">月</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: Arial; mso-font-kerning: 0pt; mso-ansi-language: en" XML:LANG="EN">22</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">日</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">报道：</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: Arial; mso-font-kerning: 0pt; mso-ansi-language: en" XML:LANG="EN">Vivus</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">公司的复合减肥药</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; FONT-FAMILY: Arial; mso-bidi-font-weight: bold" XML:LANG="EN-US">Qsiva</SPAN> <SPAN style="FONT-SIZE: 12pt; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-bidi-font-weight: bold">（</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">芬特明</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: Arial; mso-font-kerning: 0pt; mso-ansi-language: en" XML:LANG="EN">-</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">缓释托吡酯，</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: Arial; mso-font-kerning: 0pt; mso-ansi-language: en" XML:LANG="EN">phentermine+extended-release topiramate</SPAN><SPAN style="FONT-SIZE: 12pt; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-bidi-font-weight: bold">）审批没有获得欧洲药品局首肯，障碍是它的副作用问题。</SPAN></P>
<P style="BACKGROUND: white; MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 24pt; TEXT-ALIGN: left; mso-line-height-alt: 0pt; mso-char-indent-count: 2.0; mso-pagination: widow-orphan" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">该芬特明和缓释托吡酯的组合配方在今年</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: Arial; mso-font-kerning: 0pt; mso-ansi-language: en" XML:LANG="EN">7</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">月</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: Arial; mso-font-kerning: 0pt; mso-ansi-language: en" XML:LANG="EN">17</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">日获得美国</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: Arial; mso-font-kerning: 0pt; mso-ansi-language: en" XML:LANG="EN">FDA</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">批准，作为低热量饮食和体育锻炼附加措施用于肥胖患者长期体重控制。其在美国的商品名为</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: Arial; mso-font-kerning: 0pt; mso-ansi-language: en" XML:LANG="EN"><A href="http://www.drugs.com/qsymia.html"><SPAN style="COLOR: black; TEXT-DECORATION: none; text-underline: none"><FONT face=Arial>Qsymia</FONT></SPAN></A></SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">。</SPAN></P>
<P style="BACKGROUND: white; MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 24pt; TEXT-ALIGN: left; mso-line-height-alt: 0pt; mso-char-indent-count: 2.0; mso-pagination: widow-orphan" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; FONT-FAMILY: 宋体; mso-bidi-font-family: Arial; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial; mso-font-kerning: 0pt; mso-ansi-language: en">因为可能会危害胎儿，该药不得在怀孕期间使用。数据显示，在怀孕的头三个月，胎儿暴露于该药的成分之一托吡酯，唇颚裂（唇裂或腭裂）的风险增加。有生殖能力的女性在启动该药治疗前和用药期间每月作怀孕测试，并坚持采取避孕措施。另外，青光眼或甲状腺功能亢进症者不能使用该药，因为它可能加快心率。</SPAN></P> |
